906091-46-1Relevant academic research and scientific papers
Catalytic c-c cleavage/alkyne-carbonyl metathesis sequence of cyclobutanones
Gao, Jiqiang,Liu, Chunhui,Li, Zhongjuan,Liang, Haotian,Ao, Yuhui,Zhao, Jinbo,Wang, Yuchao,Wu, Yuanqi,Liu, Yu
supporting information, p. 3993 - 3999 (2020/06/08)
A ring-opening/alkyne-carbonyl metathesis sequence of alkyne-tethered cyclobutanones catalyzed by AgSbF6 is realized for the first time to furnish multisubstituted naphthyl ketones under mild conditions. A range of substrates decorated with various substituents at different positions were all well accommodated. Preliminary mechanistic studies show that silver salt acted as a Lewis acid to facilitate both C-C cleavage of the cyclobutanone moiety and the subsequent metathesis between C═O and CC bonds.
Enantioselective C-C bond cleavage creating chiral quaternary carbon centers
Matsuda, Takanori,Shigeno, Masanori,Makino, Masaomi,Murakami, Masahiro
, p. 3379 - 3381 (2007/10/03)
A chiral all-carbon benzylic quaternary carbon center is created by the asymmetric intramolecular addition/ring-opening reaction of a boryl-substituted cyclobutanone, which involves enantioselective β-carbon elimination from a symmetrical rhodium cyclobutanolate. The asymmetric reaction was successfully applied to a synthesis of sesquiterpene, (-)-α-herbertenol.
