906095-29-2

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 548-93-6 3-hydroxyanthranilic acid 

Downstream Products

• 1175526-77-8 2-p-tolylbenzo[d]oxazole-4-carboxamide 
• 1175529-62-0 methyl 2-(4-(bromomethyl)phenyl)benzo[d]oxazole-4-carboxylate 
• 1175529-61-9 methyl 2-p-tolylbenzo[d]oxazole-4-carboxylate 

Relevant academic research and scientific papers

BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)

A compound having the structure set forth in Formula (I) or Formula (II): wherein the variables Y, R1, R2, R3, and R4 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.

Benzoxazole carboxamides for treating CINV and IBS-D

Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.