90613-04-0Relevant articles and documents
Facile synthesis of 2-azaspiro[3.4]octane
Ramesh, Subbiah,Balakumar, Ramadas,Rizzo, John R.,Zhang, Tony Y.
, p. 3056 - 3065 (2019/03/21)
Our annulation strategy utilized for the synthesis of 2-azaspiro[3.4]octane is explained. Three successful routes for the synthesis were developed. One of the approaches involved annulation of the cyclopentane ring and the remaining two approaches involved annulation of the four membered ring. All three approaches employ readily available starting materials with conventional chemical transformations and minimal chromatographic purifications to afford the title compound. The merits and limitations of the three approaches are also discussed.
Hydroxypurine compound and use thereof
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Paragraph 0232; 0233; 0234; 0235, (2016/10/08)
The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.
A FACILE STEREOSELECTIVE SYNTHESIS OF +/- SESBANINE
Wanner, Martinus J.,Koomen, Gerrit-Jan,Pandit, Upendra K.
, p. 377 - 379 (2007/10/02)
10-Dehydrosesbanine (4), prepared via a sequence in which the tricyclic spiro cyclopentano-2,7-naphthyridine ring system is prepared by condensation of 3-(ethylenedioxy)cyclopentanecarboxylate ester anion with N-benzylnicotinamide, is stereoselectively re
