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DIPROTIN A is a synthetic tripeptide consisting of the amino acid sequence Ile-Pro-Ile. It functions as a dipeptidyl peptidase IV (DPP-IV) inhibitor, which plays a crucial role in regulating the activity of various peptides in the body. DIPROTIN A has gained attention for its potential applications in the medical field, particularly as an anti-cancer agent.
Used in Pharmaceutical Industry:
DIPROTIN A is used as an anti-cancer agent for its ability to inhibit DPP-IV, an enzyme that is overexpressed in various types of cancer cells. By inhibiting DPP-IV, DIPROTIN A can help regulate the activity of peptides involved in cell growth, proliferation, and metastasis, potentially leading to the suppression of tumor growth and progression.
Used in Hormone Measurement:
DIPROTIN A is used as a supplement in blood collection for hormone measurement. It helps stabilize certain peptides, such as glucagon-like peptide-1 (GLP-1), during the blood collection process, ensuring accurate hormone measurements.
Used in Islet Cell Culture:
In islet cell culture, DIPROTIN A is used to stabilize GLP-1, a peptide hormone that plays a role in glucose homeostasis. By stabilizing GLP-1, DIPROTIN A can help maintain its biological activity, which is essential for studying its role in glucose regulation and potential therapeutic applications.
Used in Endocrinology Research:
DIPROTIN A is used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection. GnIH is an important regulator of reproductive function, and its stability is crucial for accurate measurement and analysis in endocrinology research. By inhibiting its breakdown, DIPROTIN A helps maintain the integrity of GnIH, allowing for more reliable research findings.

90614-48-5

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90614-48-5 Usage

Biochem/physiol Actions

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

Check Digit Verification of cas no

The CAS Registry Mumber 90614-48-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,6,1 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 90614-48:
(7*9)+(6*0)+(5*6)+(4*1)+(3*4)+(2*4)+(1*8)=125
125 % 10 = 5
So 90614-48-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)/t10-,11-,12-,13-,14-/m0/s1

90614-48-5 Well-known Company Product Price

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  • Sigma

  • (I9759)  Ile-Pro-Ile  ≥97% (HPLC)

  • 90614-48-5

  • I9759-5MG

  • 1,368.90CNY

  • Detail

  • Sigma

  • (I9759)  Ile-Pro-Ile  ≥97% (HPLC)

  • 90614-48-5

  • I9759-25MG

  • 3,112.20CNY

  • Detail

90614-48-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name DIPROTIN A

1.2 Other means of identification

Product number -
Other names ILE-PRO-ILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90614-48-5 SDS

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