90618-60-3Relevant articles and documents
Asymmetric Syntheses. Part 11. Reduction of Ketones and Related Ketone Oximes with Lithium Aluminium Hydride-3-O-cyclohexylmethyl-1,2-O-cyclohexylidene-α-D-glucofuranose Complex to give Optically Active Alcohols and Amines
Landor, Stephen R.,Chan, Yuet M.,Sonola, Olutunji O.,Tatchell, Austin R.
, p. 493 - 496 (2007/10/02)
The asymmetric reduction of ketones and structurally related isoelectronic ketone oximes with lithium aluminium hydride-3-O-cyclohexylmethyl-1,2-O-cyclohexylidene-α-D-glucofuranose complex yields optically active alcohols of up to 42percent optical purity and optically active amines of up to 52percent optical purity, respectively.The resulting alcohols as well as amines all have the S-configuration.When the asymmetric reduction is carried out with the ethanol-modified glucofuranose complex, the resulting alcohols and amines have the R-configuration.