LATS, or large tumor suppressor, is a family of protein kinases that play a crucial role in regulating cell proliferation and tissue growth. As part of the Hippo signaling pathway, LATS proteins are instrumental in controlling organ size and suppressing tumor formation. The two main members of the LATS family, LATS1 and LATS2, are known for their ability to phosphorylate and inhibit the activity of transcriptional coactivators YAP and TAZ, which are key regulators of cell proliferation and survival. The dysregulation of LATS signaling has been associated with various diseases, particularly cancer, highlighting its potential as a target for therapeutic intervention. A deeper understanding of the function of LATS proteins and their role in cell signaling pathways may pave the way for the development of treatments for cancer and other related conditions.
9062-77-5
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Chemical Properties
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- CAS DataBase Reference: LATS(CAS DataBase Reference)
- NIST Chemistry Reference: LATS(9062-77-5)
- EPA Substance Registry System: LATS(9062-77-5)
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- Hazardous Substances Data: 9062-77-5(Hazardous Substances Data)
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9062-77-5 Usage
Uses
Used in Pharmaceutical Industry:LATS is used as a target for therapeutic intervention for cancer treatment due to its role in regulating cell proliferation and tissue growth, as well as its involvement in the Hippo signaling pathway that controls organ size and suppresses tumor formation.
Used in Cancer Research:
LATS is used as a subject of study to understand its function and role in cell signaling pathways, which may provide insights into the development of treatments for cancer and other related conditions.
Used in Drug Development:
LATS is used as a target for the development of drugs that aim to modulate its activity, potentially leading to the inhibition of tumor growth and the treatment of cancer.
Used in Diagnostics:
LATS may be used as a biomarker for the diagnosis and monitoring of cancer, as dysregulation of LATS signaling has been linked to various diseases, including cancer.
Used in Cell Biology Research:
LATS is used as a research subject to explore its role in the regulation of cell proliferation and survival, as well as its interaction with other proteins in the Hippo signaling pathway. This research may contribute to a better understanding of the molecular mechanisms underlying cancer development and progression.
Check Digit Verification of cas no
The CAS Registry Mumber 9062-77-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,6 and 2 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 9062-77:
(6*9)+(5*0)+(4*6)+(3*2)+(2*7)+(1*7)=105
105 % 10 = 5
So 9062-77-5 is a valid CAS Registry Number.
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LATS
