90629-38-2

Upstream product

• 90628-93-6 3(S)-<1(R)-<(tert-butyldimethylsilyl)oxy>ethyl>-4(R)-<<(phenylthio)carbonyl>methyl>azetidin-2-one 
• 86978-81-6 (3R,4R)-4-acetoxy-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-1-trimethylsilyl-2-azetidinone 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 

Downstream Products

• 78072-35-2 (5R,6S)-6-[(R)-1-(4-Nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-3-phenylsulfanyl-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 90629-11-1 {(3S,4R)-3-[(R)-1-(4-Nitro-benzyloxycarbonyloxy)-ethyl]-2-oxo-4-phenylsulfanylcarbonylmethyl-azetidin-1-yl}-oxo-acetic acid 4-nitro-benzyl ester 
• 90629-15-5 (3S,4R)-3-[(R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-1-[1-(p-nitrobenzyloxycarbonyl)-1-triisopropoxyphosphoranylidenemethyl]-4-[(phenylthio)carbonylmethyl]-2-azetidinone 
• 90694-08-9 (3S,4R)-3-<(R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4-<(phenylthiocarbonyl)methyl>-2-azetidinone 

Relevant academic research and scientific papers

Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics

Compounds of formula (I): STR1 (wherein R1 represents hydrogen or a hydroxy-protecting group, R2 and R3 represent hydrogen, alkyl or aryl; R4 represents optionally substituted alkyl, alicyclic heterocyclic, aryl

AN EFFICIENT CARBAPENEM SYNTHESIS VIA AN INTRAMOLECULAR WITTIG REACTION OF NEW TRIALKOXYPHOSPHORANE-THIOLESTERS

New trialkoxyphosphorane-thiolesters 10, obtained by reaction of oxalimides 9 with trialkyl phosphite, were efficiently cyclized by an intramolecular Wittig reaction to give carbapenems 11.