906329-50-8

Basic information

• Product Name: N-BOC-4-(4'-FLUORO) BENZYL-4-PIPERIDINE CARBOXYLIC ACID
• Synonyms: N-BOC-4-(4'-FLUORO) BENZYL-4-PIPERIDINE CARBOXYLIC ACID;1-BOC-4-[(4-FLUOROPHENYL)METHYL]-4-PIPERIDINECARBOXYLIC ACID;1-Boc-4-(4-fluorobenzyl)-4-piperidinecarboxylic acid
• CAS NO: 906329-50-8
• Molecular Formula: C₁₈H₂₄FNO₄
• Molecular Weight: 337.389
• Mol File: 906329-50-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 461.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.214±0.06 g/cm3(Predicted)
• PKA: 4.43±0.20(Predicted)
• CAS DataBase Reference: N-BOC-4-(4'-FLUORO) BENZYL-4-PIPERIDINE CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-4-(4'-FLUORO) BENZYL-4-PIPERIDINE CARBOXYLIC ACID(906329-50-8)
• EPA Substance Registry System: N-BOC-4-(4'-FLUORO) BENZYL-4-PIPERIDINE CARBOXYLIC ACID(906329-50-8)

Safety Data

• Hazardous Substances Data: 906329-50-8(Hazardous Substances Data)

Upstream product

• 917755-77-2 4-(4-Fluoro-benzyl)-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester 
• 906329-46-2 1-tert-butyl 4-methyl 4-(4-fluorobenzyl)piperidine-1,4-dicarboxylate 

Relevant articles and documents

SPIRO AROMATIC RING COMPOUND AND APPLICATION THEREOF

Provided is a compound of formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, isotopic substituent, polymorph, prodrug, or metabolite thereof. Also provided is a method for preparing the compound of formula I. The compound of formula I has higher inhibitory activity against SHP2, and thus can be used to prevent or treat a disease related to SHP2.