906354-75-4Relevant academic research and scientific papers
Practical and Reliable Synthesis of 1,2-Dideoxy-D-ribofuranose and its Application in RNAi Studies
Nagaya, Yuki,Kitamura, Yoshiaki,Nakashima, Remi,Shibata, Aya,Ikeda, Masato,Kitade, Yukio
, p. 64 - 75 (2016/03/01)
We developed a practical and reliable method for synthesizing an abasic deoxyribonucleoside, 1,2-dideoxy-D-ribofuranose (dRH) via elimination of nucleobase from thymidine. To synthesize oligonucleotides bearing dRH by the standard ph
Potential application of thymidylate kinase in nucleoside analogue activation in Plasmodium falciparum
Cui, Huaqing,Ruiz-Pérez, Luis M.,González-Pacanowska, Dolores,Gilbert, Ian H.
experimental part, p. 7302 - 7309 (2010/11/18)
Plasmodium falciparum thymidylate kinase (PfTMPK) shows a broad range of substrate tolerance when compared to the corresponding human enzyme. Besides 2′-deoxythymidine monophosphate (dTMP), PfTMPK can phosphorylate 3′-azido-2′,3′-dideoxythymidine monophos
