906481-17-2

Usage

Uses

Used in Organic Synthesis:
2-(4-methoxy-3-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)-ethanone is used as a key intermediate in organic synthesis for the production of various complex organic molecules. Its unique functional groups allow for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(4-methoxy-3-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)-ethanone is used as a starting material or a building block for the development of new drugs. Its potential biological activities and structural diversity make it a promising candidate for the discovery of novel therapeutic agents.

Upstream product

• 932033-69-7 2-(4-methoxy-3-nitro-benzyl)-2-(3,4,5-trimethoxy-phenyl)-[1,3]dithiane 
• 931407-28-2 [(Tetrahydro-pyran-2-yloxy)-(3,4,5-trimethoxy-phenyl)-methyl]-phosphonic acid dimethyl ester 
• 31680-08-7 4-methoxy-3-nitrobenzaldehyde 
• 130190-35-1 dimethyl α-hydroxy-α-(3,4,5-trimethoxyphenyl)methanephosphonate 
• 57009-70-8 2-(3,4,5-trimethoxyphenyl)-1,3-dithiane 

Downstream Products

• 916165-41-8 5-(4-methoxy-3-nitro-phenyl)-4-(3,4,5-trimethoxy-phenyl)-[1,2,3]thiadiazole 
• 1013401-98-3 3-dimethylamino-2-(4-methoxy-3-nitro-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone 
• 852990-42-2 1-(4-methoxy-3-nitrophenyl)-2-(3,4,5-trimethoxyphenyl)-1,2-ethanedione 
• 906481-19-4 4-(4-methoxy-3-nitro-phenyl)-5-(3,4,5-trimethoxy-phenyl)-isoxazole 
• 932033-72-2 3-dimethylamino-2-(4-methoxy-3-nitro-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 2,3-diarylthiophene analogues of combretastatin A-4

A series of novel 2,3-diarylthiophene analogues of combretastatin A-4 (CA-4) were designed with a rigid thiophene moiety to retain the cis-olefin configuration of CA-4 and were subsequently synthesised. All of the target compounds were evaluated for their

Synthesis and biological evaluation of novel 3,4-diaryl-1,2,5-selenadiazol analogues of combretastatin A-4

A set of novel selenium-containing heterocyclic analogues of combretastatin A-4 (CA-4) have been designed and synthesised using a rigid 1,2,5-selenadiazole as a linker to fix the cis-orientation of ring-A and ring-B. All of the target compounds were evalu

COMPOUNDS FOR THE TREATMENT OF ANGIOGENESIS

The invention relates to isoxazole, isothiazole, and triazole compounds that are useful for treating or inhibiting angiogenesis.

Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents

A series of 4,5-disubstitute-1,2,3-thiadiazole compounds were designed and synthesized as potent anticancer agents, some of them exhibited excellent in vitro and in vivo inhibitory activity.

Synthesis and cytotoxic activities of 4,5-diarylisoxazoles

A series of 4,5-diarylisoxazoles related to combretastatin A-4 (CA-4) were synthesized and evaluated for cytotoxicity against three human cancer cell lines. Among them, compound 6e showed better cytotoxic activity than CA-4 in HeLa and HepG2 cell lines as

COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polym