906482-23-3Relevant articles and documents
Photochemical generation of C4′-oxidized abasic site containing oligodeoxynucleotide and its efficient amine modification
Aso, Mariko,Usui, Kazuteru,Fukuda, Mitsuhiro,Kakihara, Yoshie,Goromaru, Tsuyoshi,Suemune, Hiroshi
, p. 3183 - 3186 (2007/10/03)
We synthesized oligodeoxynucleotide (ODN, 3), which contains 4′-o-nitrobenzyloxythymidine (4) as a caged precursor of C4′-oxidized abasic site (1). Photoirradiation of 3 at 365 nm followed by amine treatment under neutral conditions afforded the lactam (2