906482-48-2

Basic information

• Product Name: (-)-Varitriol
• Synonyms: (1E)-
• CAS NO: 906482-48-2
• Molecular Formula: C₁₅H₂₀O₅
• Molecular Weight: 280.3163
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 906482-48-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (-)-Varitriol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-Varitriol(906482-48-2)
• EPA Substance Registry System: (-)-Varitriol(906482-48-2)

Safety Data

• Hazardous Substances Data: 906482-48-2(Hazardous Substances Data)

Upstream product

• 1415904-95-8 methyl 2-((E)-2-((3aS,4S,6S,6aS)-6-(iodomethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)vinyl)-6-methoxybenzoate 
• 1415904-94-7 methyl 2-((E)-2-((3aS,4S,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)vinyl)-6-methoxybenzoate 
• 906102-77-0 2-[(E)-2-(2-tert-butyldimethylsilyloxymethyl-3-methoxyphenyl)styryl]-4',5'-O-isopropylidene-7'-deoxy-D-ribofuranose 

Relevant articles and documents

A conventional approach to the total synthesis of (-)-varitriol

The stereoselective total synthesis of (-)-varitriol has been achieved starting from commercially available d-(-)-ribose and o-anisic acid. A Mitsunobu reaction, Julia-Kocienski olefination, and one pot reduction of both ester and iodo functionalities with superhydride are the key reactions involved in this synthesis.

An efficient total synthesis and absolute configuration determination of varitriol

The first total synthesis and the absolute configuration determination of varitriol are described. The Royal Society of Chemistry 2006.