906545-88-8Relevant articles and documents
Stereoselective synthesis and immunogenic activity of the C-analogue of sulfatide
Modica, Emilia,Compostella, Federica,Colombo, Diego,Franchini, Laura,Cavallari, Marco,Mori, Lucia,De Libero, Gennaro,Panza, Luigi,Ronchetti, Fiamma
, p. 3255 - 3258 (2007/10/03)
The C-sulfatide 1b was synthesized through a [2,3]-Wittig sigmatropic rearrangement and a Horner-Wadsworth-Emmons olefination as the key steps. The C-analogue 1b is less immunogenic than natural sulfatide 1a, but induces a preferential secretion of the proinflammatory cytokine IFN-γ.