906669-53-2

Upstream product

• 906669-52-1 N-(2-fluorophenyl)-3-bromo-4,6-dimethoxybenzamide hydrazone 
• 530-62-1 1,1'-carbonyldiimidazole 
• 906669-52-1 N-(2-fluorophenyl)-3-bromo-4,6-dimethoxy-benzamide hydrazone 

Downstream Products

• 906669-94-1 5-[4-(2-fluoro-phenyl)-3-hydroxy-4H-[1,2,4]triazol-5-yl]-2,4-dimethoxy-5-benzoic acid methyl ester 
• 906669-55-4 C₂₄H₂₀FN₃O₃ 
• 906669-54-3 C₂₄H₂₀FN₃O₃ 

Relevant academic research and scientific papers

TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR

5-[4-(2-Methylphenyl)-3-hydroxy-4H-1,2,4-triazol-5-yl]-2,4-dihydroxy-N-methyl-N-butylbenzamide is an HSP90 inhibitor and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

TRIAZOLE DERIVATIVES

The invention relates to novel triazole derivatives of formula (I) wherein R1 - R6 and Y have the designations cited in patent claim 1. Said derivatives are HSP90 inhibitors, and can be used to produce a medicament for treating diseases wherefore the inhibition, regulation and/or modulation of HSP90 plays an important role.