90689-39-7

Usage

Uses

Used in Pharmaceutical Research:
(1-Oxo-1H-phthalazin-2-yl)-acetic acid is used as a building block in the synthesis of various organic compounds for pharmaceutical research. Its unique structure and potential biological activities make it an interesting target for the development of new pharmaceutical drugs.
Used in Organic Synthesis:
In the field of organic synthesis, (1-Oxo-1H-phthalazin-2-yl)-acetic acid is used as a key intermediate for the synthesis of a wide range of organic compounds. Its versatile chemical properties allow it to be incorporated into various molecular structures, making it a valuable component in the creation of new chemical entities.

Upstream product

• 18584-72-0 1(2H)-oxophthalazin-2-acetic acid ethyl ester 
• 119-39-1 phthalazone 
• 79-08-3 bromoacetic acid 

Relevant academic research and scientific papers

Phthalazinone in heterocyclic synthesis: Synthesis of some s-triazole, s-triazolothiadiazine, s-triazolothiadiazine, and s-triazolothiadiazole derivatives as pharmaceutical interest

1(2H)-Oxophthalazine-2-acetic acid ethyl ester was allowed to react with various reagents under different conditions to yield compounds 2-[(4-substituted-5-mercaptotriazol-3-yl) methyl]-1(2H)-oxophthalzines 5 and 7 which acted as starting materials for the preparation of some new s-triazolo[5,1-b][1,3]thiazine (8), s-triazolo[3,4-b][1,3,4]thiadiazine 9,12,14,20, and s-triazolo[3,4-b][1,3,4]thiadiazole 18,21 derivatives.

Annulation to the Phthalazine Ring System Utilizing Mesoionic Ring Systems

anhydro-3-Hydroxy-2-phenylthiazolophthalizinium hydroxide, prepared from 1(2H)-phthalazinethione and α-bromophenylacetyl chloride or by Ac2O/Et3N ring closure of S-(1-phthalazinyl)-α-phenylthioglycolic acid, and dimethyl acetylenedicarboxylate in r