907172-87-6

Basic information

• Product Name: C₁₃H₂₃NO₂
• CAS NO: 907172-87-6
• Molecular Weight: 225.331
• Mol File: 907172-87-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₂₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₂₃NO₂(907172-87-6)
• EPA Substance Registry System: C₁₃H₂₃NO₂(907172-87-6)

Safety Data

• Hazardous Substances Data: 907172-87-6(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 286-20-4 cyclohexane-1,2-epoxide 
• 7581-94-4 (+)-trans-(1-Piperidyl)cyclohexan-2-ol 
• 108-24-7 acetic anhydride 

Relevant articles and documents

In vivo antifilarial activity of some cyclic and acylic alcohols

The filarial nematodes, Wuchereria bancrofti, Brugia malayi, and Brugia timori are the causative agents of lymphatic filariasis. 2-Substituted propanol, cyclohexanol, and cyclooctanol compounds were evaluated for microfilaricidal and macrofilaricidal activity in vivo against Acanthocheilonema viteae and Litomosoides carinii in rodents. In the cyclohexanol series, 2-(piperidin-1-yl) cyclohexanol (2b) showed 88.9% macrofilaricidal activity against A. viteae in vivo, while cyclooctanol series, 2-(4- benzyl piperdin-1-yl) cyclooctanol (2f) showed 100% macrofilaricidal activity against A. viteae. Further, compounds 1-(furan-2-ylamino) ethanol (4a) and 1-(4-benzylpiperidin- 1-yl)-ethyl acetate (5b) showed 81.3% and 83.4% macrofilaricidal activity, respectively, against the same parasite. Interestingly, compounds 2f and 4a showed significant sterilization of female worms in A. viteae. However, these compounds were found inactive against L. carinii. Therefore, the new class of compounds appeared to have promising antifilarial activity.