90721-58-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Methyl 2-bromo-5-(bromomethyl)benzoate is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique chemical structure allows for the development of new compounds with potential therapeutic and pesticidal properties.
Used in Organic Synthesis:
In the field of organic synthesis, Methyl 2-bromo-5-(bromomethyl)benzoate serves as a reagent for a wide range of chemical reactions. Its versatility enables the creation of diverse organic compounds for various applications.
Used in Medicinal Chemistry and Drug Development:
Due to its chemical properties, Methyl 2-bromo-5-(bromomethyl)benzoate has potential applications in medicinal chemistry and drug development. Researchers can utilize Methyl 2-broMo-5-(broMoMethyl)benzoate to design and synthesize new drugs with improved efficacy and safety profiles.
Safety Precautions:
It is crucial to handle and store Methyl 2-bromo-5-(bromomethyl)benzoate with proper safety measures, as it can be hazardous if not used or handled correctly. Following safety guidelines and protocols ensures the protection of individuals and the environment.

Upstream product

• 90971-88-3 methyl 2-bromo-5-methylbenzoate 

Downstream Products

• 1187238-21-6 2-bromo-5-(hydroxymethyl)benzoic acid 
• 1239956-64-9 methyl 2-bromo-5-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro-3-methoxyphenyl)-1H-imidazol-2-ylthio)methyl)benzoate 
• 1239957-13-1 amino(3-(2-carboxy-4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro-3-methoxyphenyl)-1H-imidazol-2-ylthio)methyl)phenyl)propylamino)methaniminium 2,2,2-trifluoroacetate 
• 1239963-54-2 methyl 5-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro-3-methoxyphenyl)-1H-imidazol-2-ylthio)methyl)-2-(3-guanidinopropyl)benzoate 
• 1239957-07-3 methyl 5-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro-3-methoxyphenyl)-1H-imidazol-2-ylthio)methyl)-2-(3-hydroxypropyl)benzoate 
• 1239963-49-5 methyl 5-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluoro-3-methoxyphenyl)-1H-imidazol-2-ylthio)methyl)-2-(3-hydroxyprop-1-ynyl)benzoate 
• 1261638-98-5 C₂₃H₂₂BrNO₅S 

Relevant academic research and scientific papers

Identification and structure–activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus

Our previously reported carboxyl-containing DPP-4 inhibitors were highly potent but were poorly bioavailable. Esters of the carboxyl analogs exhibited a significant DPP-4 potency loss albeit with enhanced oral absorption. Herein, we described identificati

Design, synthesis and identification of novel colchicine-derived immunosuppressant

Synthesis and biological evaluation of various colchicine analogues through the mixed-lymphocyte reaction (MLR), lymphoproliferation, and inhibitory effects on the inflammatory genes are described. In addition, a new series of immunosuppressive agents developed on the structural basis of colchicine, as well as their structure-activity relationships is reported. The most potent analogue 20a exhibited an excellent immunosuppressive activity on in vivo skin-allograft model, which is comparable to that of cyclosporin A.

RENIN INHIBITORS

The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as wel

2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS

The invention relates to 2-sulfanyl-benzoimidazol-1-yl-acetic acid derivatives and their use as potent "chemoattractant receptor-homologous molecule expressed on Th2 cells" antagonists in the treatment of prostaglandin mediated diseases, to pharmaceutical compositions containing these derivatives and to processes for their preparation.

Pyrimidin derivatives

The invention relates to new pharmaceutically active compounds which are are P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists, compositions containing them and processes for their preparation.