90723-87-8

Upstream product

• 79-19-6 thiosemicarbazide 
• 74169-00-9 (2,4-dichlorophenyl)methylene-2-methyl-5(4H)-oxazolone 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Downstream Products

• 1217364-29-8 C₂₀H₁₁Cl₂N₃O₄S 
• 1217364-31-2 C₂₂H₁₇Cl₂N₃O₅S 
• 1217364-26-5 C₁₉H₁₀Cl₃N₃O₂S 
• 1217364-27-6 C₂₀H₁₃Cl₂N₃O₃S 
• 1217364-28-7 C₁₉H₉Cl₄N₃O₂S 
• 1217364-30-1 C₂₁H₁₅Cl₂N₃O₄S 
• 1256383-10-4 C₁₈H₁₂Cl₃N₃O₂S 
• 1256383-11-5 C₁₈H₁₂BrCl₂N₃O₂S 
• 1256383-12-6 C₁₉H₁₅Cl₂N₃O₃S 
• 1256383-14-8 C₁₈H₁₀Cl₄FN₃O₂S 

Relevant academic research and scientific papers

Synthesis and antimicrobial studies of thiazolotriazinones

A series of 6-substitutedphenyl thiazolo-1,2,4-triazinones (8) were obtained by the initial reaction of 6-substituted arylmethyl-3-mercapto-1,2,4- triazin-5-ones (5) with substituted phenacyl bromides (6) and further followed by PPA cyclization. The struc

Synthesis and antimicrobial evaluation of halogen-containing arylidene thiazolo triazinediones

A series of 7-substituted arylidene-1,3-thiazolo[2,3-c]-1,2,4-triazine-4,6- diones were synthesized in an one-pot multicomponent reaction of 6-arylmethyl-3-mercapto-1,2,4-triazin-5-ones with substituted benzaldehydes and monochloroacetic acid in the presence of acetic anhydride, acetic acid, and sodium acetate. The structures of the new compounds were supported by IR, 1H NMR, MS, and analytical data. All the new compounds were tested for their antibacterial and antifungal activity. Arylidene thiazolo triazinediones with 1,3-benzodioxolo substituent at seventh and p-chlorophenyl or 2,4-dichlorophenyl substituents at third displayed good antibacterial and antifungal activity. And also compound bearing 2,3,5-trimethoxyphenyl substituent at seventh and 2,4-dichlorophenyl substituent at third displayed good activity.

A novel three-component synthesis of triazinothiazolones

A series of 4-arylidene-2-methyloxazol-5-ones 1 were condensed with thiosemi-carbazide to yield 6-arylmethyl-3-mercapto-1,2,4-triazin-5-ones 2. The resulting mercapto triazinones 2 were condensed with monochloroacetic acid and 5-aryl-furan-2-carboxaldehydes 3 in a one-pot three-component reaction in the presence of acetic anhydride, acetic acid, and sodium acetate to yield 4-substituted-5-oxo-7-(5-aryl-2-furfurylidene)-1,2,4-triazino[3,4-b] -thiazol-6-ones 4. Some of the newly synthesized compounds were tested for their antibacterial activity against Gram (+)ve and Gram (-)ve bacteria. The results of such studies are discussed in this paper. Copyright Taylor & Francis, Inc.