90725-41-0

Upstream product

• 3964-56-5 4-bromo-2-chlorophenol 
• 84109-21-7 1-(allyloxy)-4-bromo-2-chlorobenzene 

Downstream Products

• 1426321-05-2 4-bromo-2-chloro-6-(3-hydroxypropyl)phenol 
• 1426320-89-9 4-bromo-2-chloro-6-(2-hydroxyethyl)phenol 
• 872518-71-3 tert-butyl (5-bromo-7-chloro-2,3-dihydrobenzofuran-2-yl)methylcarbamate 

Relevant academic research and scientific papers

MULTICYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to multicyclic compounds containing a urea or a guanidine moiety, or pharmaceutically acceptable salts or compositions thereof represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof and pharmaceutical comopositions comprising the multicyclic compounds. The invention also relates to a method for treating a disease or disorder selected from cancer (e.g., lymphoma, such as mantle cell lymphoma), a neurodegenerative disease, an inflammatory diseases or an immune system disease (e.g., a T-Cell mediated autoimmune disesase) in a subject in need thereof. The method comprises administering to a subject in need thereof a therapeutically effective amount of a compound of the invention, or a pharmaceutically acceptable salt thereof, or a composition comprising a compound of the invention, or a pharmaceutically acceptable salt thereof.

KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and diso