90725-44-3Relevant academic research and scientific papers
Synthesis of Oxazine, Thiazine, and Quinoxaline Derivatives Containing a Benzyl Fragment from 3-Aryl-2-Bromopropanoic Acids and Their Esters
Martyak, R. L.,Matiychuk, V. S.,Obushak, M. D.,Pokhodylo, N. T.,Rogovyk, M. P.
, p. 532 - 539 (2021/06/01)
Abstract: 3-Aryl-2-bromopropanoic acid esters reacted with o-phenylenediamine, 2-sulfanylaniline, and L-cysteine to give quinoxaline, 1,4-thiazine, and thiomorpholine derivatives, respectively, containing an aryl-methyl substituent. Analogous 1,4-benzoxaz
NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH
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Paragraph 0412, (2019/07/03)
Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.
