90729-01-4

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 1,4-dimethylpiperazine-2-carboxylate is used as a drug intermediate for its potential applications in the synthesis of pharmaceutical drugs. It serves as a building block in the development of new medications due to its unique molecular structure and potential therapeutic properties.
Ethyl 1,4-dimethylpiperazine-2-carboxylate is also used as a research compound for studying its possible biological activities and therapeutic properties. Its exploration in the laboratory setting is crucial for understanding its potential applications in medicine and ensuring the safety and efficacy of any resulting pharmaceutical products.

InChI:InChI=1/C9H18N2O2/c1-4-13-9(12)8-7-10(2)5-6-11(8)3/h8H,4-7H2,1-3H3

Upstream product

• 3674-13-3 2,3-dibromopropionic acid ethyl ester 
• 110-70-3 N,N`-dimethylethylenediamine 

Relevant academic research and scientific papers

Hybridized and isosteric analogues of N1-acetyl-N4-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action

A series of piperazine derivatives, obtained by hybridization of N1-acetyl-N4-dimethyl-piperazinium iodide (1, ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (3, DMPP) or of the corresponding tertiary bases (2, 4) with arecoline (5) and arecolone (6) or by isosteric substitution of the phenyl ring of DMPP, has been synthesized. Hybridization afforded compounds that, both as tertiary bases and as iodomethylates, have no affinity for the nicotinic receptor. On the contrary, isosteric substitution gave compounds that maintain affinity for the receptor; among them, two tertiary bases (37, 38), show affinity in the nanomolar range for the nicotinic receptor. The pharmacological profile of these isomeric compounds is quite interesting as they present differences in their peripheral and central effects, suggesting that they interact with different subtypes of the nicotinic receptor. Copyright (C) 1999 Elsevier Science Ltd.

3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles

2-R2 -R4 -substituted-3-R3 -CO-1-[(C-attached-N-herteryl)-(Alk)n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.