90730-94-2Relevant academic research and scientific papers
Method for administering ethanolamine derivatives to livestock
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, (2008/06/13)
A method for increasing the weight gain and/or improving the feed utilization efficiency of livestock is described which comprises the oral or non-oral administration to livestock of an effective, non-toxic amount of a compound of formula (XX): STR1 or a salt thereof, in which W is phenyl optionally substituted by halogen or trifluoromethyl, or a benzofuran-2-yl group, R1x is hydrogen or methyl, R2x is carboxyl or a group O--Z4 --CO2 H or an ester or amide thereof; a group O--E1 --NR3x R4x or a group O--E1 --OR5x, wherein R3x, R4x and R5x each represents hydrogen or C1-6 alkyl, Z4 is a C1-6 straight or branched alkylene chain, x is 1 or 2, y is 2 or 3, and E1 is C2-7 straight or branched alkylene chain with at least two carbon atoms separating the two heteroatoms in the group R2x. Also described is a veterinarily acceptable premix formulation administrable in a veterinarily effective amount in feed or water comprising a compound of the formula (XX) or, where appropriate, a veterinarily acceptable salt, ester or amide thereof; in association with a veterinarily acceptable carrier therefor. Additionally, a veterinarily acceptable premix formulation comprising from about 0.001% to about 95% by weight of a compound of formula (XX) administrable in feed or water or, where appropriate, a veterinarily acceptable salt, ester or amide thereof, together with a veterinarily acceptable carrier.
Secondary amines, their preparation and use in pharmaceutical compositions
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, (2008/06/13)
The compounds of the formula (II): STR1 and their pharmaceutically acceptable salts wherein R1 is a hydrogen, fluorine or chlorine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine or chlorine atom or a hydroxyl group; R3 is a hydrogen or chlorine atom or a hydroxyl group; R4 is a carboxylic acid group or a salt, ester or amide thereof; R5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R6 is a hydrogen atom or a methyl, or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond have been found to possess anti-obesity and/or antihyperglycaemic activity.
