90732-06-2

Basic information

• Product Name: 1(4H)-Pyridinecarboxylic acid, 4-cyclohexyl-3-(1,3-dioxolan-2-yl)-, phenyl ester
• CAS NO: 90732-06-2
• Molecular Formula: C21H25NO4
• Molecular Weight: 355.434
• Mol File: 90732-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(4H)-Pyridinecarboxylic acid, 4-cyclohexyl-3-(1,3-dioxolan-2-yl)-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1(4H)-Pyridinecarboxylic acid, 4-cyclohexyl-3-(1,3-dioxolan-2-yl)-, phenyl ester(90732-06-2)
• EPA Substance Registry System: 1(4H)-Pyridinecarboxylic acid, 4-cyclohexyl-3-(1,3-dioxolan-2-yl)-, phenyl ester(90732-06-2)

Safety Data

• Hazardous Substances Data: 90732-06-2(Hazardous Substances Data)

Upstream product

• 5740-72-7 3-(ethylenedioxymethyl)pyridine 
• 931-51-1 cyclohexylmagnesiumchloride 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 90732-11-9 4-Cyclohexyl-3-[1,3]dioxolan-2-yl-pyridine 

Relevant articles and documents

SYNTHESIS OF 3-HALO- AND 3-FORMYL-4-ALKYLPYRIDINES

In the presence of a catalytic amount of cuprous iodide, the addition of Grignard reagents to the 1-phenoxycarbonyl salts of 3-halopyridines gives 4-alkyl-3-halo-1-phenoxycarbonyl-1,4-dihydropyridines.The crude dihydropyridines were aromatized with o-chloroanil to give 4-alkyl-3-halopyridines.Several 4-alkylnicotinaldehydes were synthesized in a similar manner from the cyclic acetal (1,3-dioxolane) of 3-pyridinecarboxaldehyde.After aromatization with sulfur, the crude acetals were hydrolyzed with oxalic acid to give the desired pyridinecarboxaldehydes.