Pyroglutamyl peptidase I, also known as E. coli pyroglutamyl aminopeptidase, is an enzyme derived from Escherichia coli bacteria. It plays a crucial role in the degradation of N-terminal pyroglutamate residues in proteins and peptides. This enzyme is involved in the regulation of protein stability and function, as well as in the processing of certain neuropeptides. Pyroglutamyl peptidase I is a zinc metalloenzyme, which means it requires zinc ions for its catalytic activity. It has been studied for its potential applications in the pharmaceutical industry, particularly in the development of drugs targeting neuropeptide systems. The enzyme's ability to cleave pyroglutamate residues makes it a valuable tool in the study of protein structure and function, as well as in the development of therapeutic strategies for various diseases.
Synonyms: PYROGLUTAMAT AMINOPEPTIDASE FROM E. COLI;pyroglutamate aminopeptidase from calf liver;Pyroglutamate Aminopeptidase from E. coli;Aminopeptidase, pyroglutamate;PYROGLUTAMAT-AMINOPEPTIDASE FROM BACILLUS SP.;PYROGLUTAMAT AMINOPEPTIDASE FROM E. COLI PGE WITH 0.01 UNIT;Pyrase, Pyroglutamyl-Peptidase I, Pyrrolidone Carboxyl Peptidase;Pyroglutamate Aminopeptidase from Pyrococcus furiosus, recombinant from E. coli
The CAS Registry Mumber 9075-21-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively. Calculate Digit Verification of CAS Registry Number 9075-21: (6*9)+(5*0)+(4*7)+(3*5)+(2*2)+(1*1)=102 102 % 10 = 2 So 9075-21-2 is a valid CAS Registry Number.
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