907548-13-4Relevant academic research and scientific papers
Synthesis and biological activity of 1-cyclopropyl-1,4-dihydro-4-oxo-3- pyridinecarboxylic acid
Pfaendler, Hans Rudolf,Jenni, Wolfgang
, p. 867 - 874 (1999)
1-Cyclopropyl-1,4-dihydro-4-oxo-3-pyridinecarboxylic acid was prepared in four reaction steps and tested for antibacterial activity.
An efficient ZrCl4 catalyzed aza-michael addition reaction: Synthesis of C-linked carbo β3-amino acids
Damera, Krishna,Reddy, Katta L.,Sharma, Gangavaram V.M.
experimental part, p. 151 - 155 (2010/04/23)
A mild aza-Michael protocol has been developed using ZrCl4 as catalyst on α, β-unsaturated esters and nitriles. The aromatic amines were found to give the products with ease. The ZrCl4 mediated route was compatible with acid sensitive carbohydrate esters and provided an efficient method to prepare C-linked carbo β3-amino acids (β3-Caa).
