90767-17-2

Basic information

• Product Name: 3-Bromo-1-hydroxynaphthalene
• Synonyms: 3-Bromo-1-hydroxynaphthalene;3-bromonaphthalen-1-ol
• CAS NO: 90767-17-2
• Molecular Formula: C₁₀H₇BrO
• Molecular Weight: 223.06598
• Mol File: 90767-17-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 61 °C
• Boiling Point: 346.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.614±0.06 g/cm3(Predicted)
• PKA: 8.59±0.40(Predicted)
• CAS DataBase Reference: 3-Bromo-1-hydroxynaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-1-hydroxynaphthalene(90767-17-2)
• EPA Substance Registry System: 3-Bromo-1-hydroxynaphthalene(90767-17-2)

Safety Data

• Hazardous Substances Data: 90767-17-2(Hazardous Substances Data)

Usage

General Description

3-Bromo-1-hydroxynaphthalene is a chemical compound with the molecular formula C10H7BrO. It consists of a naphthalene ring with a hydroxyl group and a bromine atom attached. 3-Bromo-1-hydroxynaphthalene is used as a building block in organic synthesis, particularly in the production of various pharmaceuticals and agrochemicals. It is also used in research and development as a reagent in chemical reactions and as a starting material for the synthesis of more complex organic compounds. Additionally, 3-Bromo-1-hydroxynaphthalene has potential applications in the field of material science and nanotechnology due to its unique chemical properties. However, it is important to handle this compound with care as it can be hazardous if not properly managed.

Upstream product

• 776-34-1 1-amino-4-nitronaphthalene 
• 580-13-2 2-bromonaphthalene 
• 13802-40-9 1-Methoxy-3-nitronaphthalene 
• 102153-47-9 3-bromo-1-nitronaphthalene 
• 63240-26-6 2-bromo-4-nitronaphthalen-1-amine 
• 90766-34-0 3-bromonaphthalen-1-amine 

Downstream Products

• 30069-65-9 3-phenylnaphthalen-1-ol 
• 850650-61-2 3-phenylnaphthalene-1-yl trifluoromethanesulfonate 

Relevant articles and documents

Substituent-induced regioselective hydroxylation of the aromatic C-H bond on naphthalene with metachloroperbenzoic acid catalyzed by F20TPPMnCl

The regioselective hydroxylation of the aromatic C-H bond on a series of naphthalenes with different β-substituent R (R = H, Me, Et, i-Pr, OMe, COOH, Br, etc.) was studied, and the substituent effect on the regioselectivity was investigated. The electron-donating substituent afforded the aromatic C-H bond hydroxylation at the 1α position with more than 80% selectivity, while the electron-withdrawing substituent afforded the aromatic C-H bond hydroxylation at the 4α position with more than 60% selectivity of β-substituted naphthalene hydroxylated with metachloroperbenzoic acid catalyzed by tetrakis(pentafluorophenyl)porphyrin manganese(III) chloride. The research showed that the steric and electronic effects of the substituent appeared to play a significant role in determining the regioselectivity, and the electronic effect was of more importance than the steric effect of the substituent in the current situation. The studies may provide additional proofs for the stepwise mechanism of the aromatic C-H bond hydroxylation through a cationic intermediate. Copyright

SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS

The present invention relates to compounds of formula (I) wherein R1 to R8 and n are as defined in the description and claims, and pharmaceutically acceptable salts and esters thereof. The compounds are useful for the treatment of diseases such as diabetes.