90771-02-1 Usage
Uses
Used in Pharmaceutical Synthesis:
Quinoline, 6-methyl-3-nitrois utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
Quinoline, 6-methyl-3-nitroserves as a key intermediate in the production of agrochemicals, contributing to the development of pesticides and other agricultural products designed to protect crops and enhance yields.
Used in Dye and Pigment Manufacturing:
Quinoline, 6-methyl-3-nitrois employed in the manufacturing of dyes and pigments due to its color-producing properties, which are valuable in a variety of industries, including textiles, paints, and plastics.
Used in Biological and Pharmacological Research:
Due to its potential anti-inflammatory and antimicrobial properties, Quinoline, 6-methyl-3-nitrois used in research to explore its efficacy in treating various diseases and conditions, potentially leading to new treatments and therapies.
It is crucial to handle Quinoline, 6-methyl-3-nitrowith care, as it may present health and environmental risks if not properly managed. Safety measures should be taken to minimize exposure and ensure the responsible use of this chemical compound in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 90771-02-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,7,7 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 90771-02:
(7*9)+(6*0)+(5*7)+(4*7)+(3*1)+(2*0)+(1*2)=131
131 % 10 = 1
So 90771-02-1 is a valid CAS Registry Number.
90771-02-1Relevant academic research and scientific papers
meta-Nitration of Arenes Bearing ortho/para Directing Group(s) Using C?H Borylation
Li, Xuejing,Deng, Xingwang,Coyne, Anthony G.,Srinivasan, Rajavel
supporting information, p. 8018 - 8023 (2019/05/29)
Herein, we report the meta-nitration of arenes bearing ortho/para directing group(s) using the iridium-catalyzed C?H borylation reaction followed by a newly developed copper(II)-catalyzed transformation of the crude aryl pinacol boronate esters into the corresponding nitroarenes in a one-pot fashion. This protocol allows the synthesis of meta-nitrated arenes that are tedious to prepare or require multistep synthesis using the existing methods. The reaction tolerates a wide array of ortho/para-directing groups, such as ?F, ?Cl, ?Br, ?CH3, ?Et, ?iPr ?OCH3, and ?OCF3. It also provides regioselective access to the nitro derivatives of π-electron-deficient heterocycles, such as pyridine and quinoline derivatives. The application of this method is demonstrated in the late-stage modification of complex molecules and also in the gram-scale preparation of an intermediate en route to the FDA-approved drug Nilotinib. Finally, we have shown that the nitro product obtained by this strategy can also be directly converted to the aniline or hindered amine through Baran's amination protocol.
IMIDAZO[4,5-B]QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS
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Page 20, (2010/02/08)
The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
