90771-20-3

Basic information

• Product Name: (5Z)-5-[(2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione
• Synonyms: (5Z)-5-(2-hydroxybenzylidene)imidazolidine-2,4-dione; 2,4-imidazolidinedione, 5-[(2-hydroxyphenyl)methylene]-, (5Z)-
• CAS NO: 90771-20-3
• Molecular Formula: C₁₀H₈N₂O₃
• Molecular Weight: 204.1821
• Mol File: 90771-20-3.mol
• Article Data: 6

Chemical Properties

• Density: 1.458g/cm³
• Refractive Index: 1.686
• CAS DataBase Reference: (5Z)-5-[(2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (5Z)-5-[(2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione(90771-20-3)
• EPA Substance Registry System: (5Z)-5-[(2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione(90771-20-3)

Safety Data

• Hazardous Substances Data: 90771-20-3(Hazardous Substances Data)

Usage

General Description

The chemical compound "(5Z)-5-[(2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione" is a heterocyclic compound with an imidazolidine-2,4-dione core containing a hydroxyphenyl group. It is also known as Diaminodiphenylmethane amidel. This molecule has several potential applications, including in the pharmaceutical industry and as a chemical intermediate for the synthesis of various organic compounds. It may also have potential use in agricultural and industrial applications due to its unique structural properties and reactivity. However, further research and testing are needed to fully understand and harness its potential uses.

Upstream product

• 461-72-3 2,4-imidazolidinedione 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 
• 139554-59-9 (E)-5-(2-hydroxybenzylidene)imidazolidine-2,4-dione 
• 123-08-0 4-hydroxy-benzaldehyde 
• 95378-36-2 diethyl 2,4-dioxoimidazolidin-5-yl-phosphonate 

Relevant articles and documents

New compounds having skin whitening, antioxidant and PPAR activity, and medical use thereof

PURPOSE: A novel compound with skin whitening, antioxidation, and PPAR activation effects, and a medical use thereof are provided to be used for a pharmaceutical composition or a cosmetic product. CONSTITUTION: A compound is denoted by chemical formula 1. A skin whitening composition contains the compound as an active ingredient. An antioxidative composition for preventing or treating oxidative diseases contains the compound of chemical formula 1 as an active ingredient. The oxidative diseases are selected among skin aging, pigmentation, wrinkling, psoriasis, or eczema. The composition prevents or treats diseases which are regulated by PPAR(peroxisome proliferator-activated receptor) activity. The PPAR includes PPAR alpha or PPAR gamma.

NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR

Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.

Anticonvulsant Activity of Phenylmethylenehydantoins: A Structure-Activity Relationship Study

Phenylmethylenehydantoins (PMHs) and their des-phenyl analogues were synthesized and evaluated for anticonvulsant activity using the maximal electroshock seizure (MES) assay. The phenyl rings of PMHs were substituted with a wide spectrum of groups, and th