90772-49-9

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 103-79-7 1-phenyl-acetone 
• 24774-61-6 N-(bromomethylene)-N-methylmethanaminium bromide 

Downstream Products

• 94223-24-2 E,E-4-bromo-1,3-diphenylpenta-1,3-diene 
• 94223-24-2 E,Z-and Z,Z-4-bromo-1,3-diphenylpenta-1,3-diene 
• 94223-24-2 Z,Z-4-bromo-1,3-diphenylpenta-1,3-diene 
• 94223-49-1 (2Z,4E)-2-methyl-3,5-diphenylpenta-2,4-dienal 
• 94223-12-8 (2E,4E)-3,5-diphenyl-2-methylpenta-2,4-dienal 
• 94223-50-4 Z,E-3,5-diphenyl-2-methylpenta-2,4-dienal tosylhydrazone 
• 94078-35-0 E,E-3,5-diphenyl-2-methylpenta-2,4-dienal tosylhydrazone 

Relevant academic research and scientific papers

DERIVATIVES OF PYRROLOIMIDAZOLE OR ANALOGUES THEREOF WHICH ARE USEFUL FOR THE TREATMENT OF INTER ALIA CANCER

Present invention relates to novel heterocyclic compounds as indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) modulators. Compounds of the present invention inhibit tryptophan degradation by modulating IDO and/or TDO. Formula (I) The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3- dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of conditions that benefits from the inhibition of tryptophan degradation.