908-54-3 Usage
Description
Diminazene is a diamidine that is cytotoxic to protozoa, including Trypanosoma, Babesia, and Cytauxzoon. Diamidines, including diminazene, affect a variety of enzymes and modulate interactions between nucleic acids and proteins. Diminazene inhibits diamine oxidase with a Ki value of 13 nM. In Trypanosoma, transport proteins are important in the effectiveness of diminazene. In rats and in vitro, diminazene enhances the enzymatic activity of angiotensin-converting enzyme 2.
Chemical Properties
solid
Uses
Different sources of media describe the Uses of 908-54-3 differently. You can refer to the following data:
1. Diminazene aceturate is an anti-protozoal drug. Diminazene Diaceturate is used as an anti-trypanosomal agent.
2. antiprotozoal as aceturate
3. An anti-protozoal and anti-trypanosomal compound
Definition
ChEBI: An N-acetylglycinate salt resulting from the reaction of diminazene with 2 mol eq. of N-acetylglycine.
Veterinary Drugs and Treatments
Diminazene is used to treat trypanosomiasis in dogs and livestock
(sheep, goats, cattle), Babesia infections in dogs and horses, and cytauxzoonosis
in cats. The drug is not commercially available in the
USA, but is available and used in many countries.
Check Digit Verification of cas no
The CAS Registry Mumber 908-54-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,0 and 8 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 908-54:
(5*9)+(4*0)+(3*8)+(2*5)+(1*4)=83
83 % 10 = 3
So 908-54-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H15N7.2C4H7NO3/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18;2*1-3(6)5-2-4(7)8/h1-8H,(H3,15,16)(H3,17,18)(H,19,20);2*2H2,1H3,(H,5,6)(H,7,8)
