908009-89-2

Upstream product

• 908009-82-5 2-(biphenyl-2-yl)-6-(phenylsulfonyl)-5,6,7,8-tetrahydro-3H-quinazolin-4-one 
• 908009-75-6 3-(biphenyl-2-yl)-2,4-diazabicylo[4.2.0]octa-1⁽⁶⁾,2-dien-5-one 
• 24973-49-7 biphenyl-2-carbonitrile 
• 175692-06-5 <1,1'>-biphenyl-2-carbamidine 

Relevant academic research and scientific papers

TETRAHYDRO- AND DIHYDROQUINAZOLINONES

The present invention relates to the use of tetrahydro- and dihydroquinazolinones of formula (I) as protein kinase activators or inhibitors, a method for their manufacture, their use for the preparation of a medicament for the treatment of diseases, their

Access to variously substituted 5,6,7,8-tetrahydro-3H-quinazolin-4-ones via Diels-Alder adducts of phenyl vinyl sulfone to cyclobutene-annelated pyrimidinones

Under basic conditions (Et3N, dioxane), the aromatic amidines 4 and also S-methylisothiourea 4g cleanly undergo Michael addition to methyl 2-chloro-2-cyclopropylideneacetate (5), followed by intramolecular nucleophilic substitution, cyclopropyl