908079-30-1Relevant articles and documents
Synthesis of alkyl 6-methyl-4-(2-trifluoromethylphenyl)-1,2,3,4-tetrahydro- 2H-pyrimidine-2-one-5-carboxylates possessing a N-3 nitro substituent to determine calcium channel modulation structure-activity relationships
Kaur, Kuljeet,Knaus, Edward E.
, p. 669 - 672 (2008/09/17)
(Chemical Equation Presented) The Bigenelli acid catalyzed condensation of 2-trifluoromethylbenzaldehyde (1), urea (2) and an alkyl acetoacetate (3) afforded the respective alkyl (Me, Et, i-Pr, i-Bu) 6-methyl-4-(2- trifluoromethylphenyl)-1,2,3,4-tetrahydr