90812-24-1

Basic information

• Product Name: 3-(1-Aminoethyl)adamantan-1-ol
• Synonyms: 3-(1-Aminoethyl)adamantan-1-ol;tricyclo[3.3.1.1~3,7~]decan-1-ol, 3-(1-aminoethyl)-;3-Hydroxy Rimantadine;3-(1-aminoethyl)adamantan-1-ol(SALTDATA: HCl);3-(1-AMinoethyl)tricyclo[3.3.1.13,7]decan-1-ol
• CAS NO: 90812-24-1
• Molecular Formula: C₁₂H₂₁NO
• Molecular Weight: 195.3
• Product Categories: Amines;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 90812-24-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 298.1°C at 760 mmHg
• Flash Point: 134.1°C
• Appearance: /
• Density: 1.181g/cm³
• Vapor Pressure: 0.000131mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 3-(1-Aminoethyl)adamantan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-Aminoethyl)adamantan-1-ol(90812-24-1)
• EPA Substance Registry System: 3-(1-Aminoethyl)adamantan-1-ol(90812-24-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 90812-24-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H21NO/c1-8(13)11-3-9-2-10(4-11)6-12(14,5-9)7-11/h8-10,14H,2-7,13H2,1H3

Upstream product

• 13392-28-4 rimantadine 
• 127619-43-6 N-[1-(adamantan-1-yl)ethyl]acetamide 
• 42711-75-1 3-hydroxyadamantane-1-carboxylic acid 
• 1501-84-4 rimantadine hydrochloride 
• 127619-44-7 N-<1-(3-bromo-1-adamantyl)ethyl>acetamide 
• 39917-38-9 1-hydroxy-3-acetyladamantane 

Relevant articles and documents

Selective hydroxylation of adamantane and its derivatives

A general method was developed for hydroxylation into the nodal position of adamantane and its 1- and 2-substituted derivatives employing systems H 2O-CBr4 (BrCCl3, CCl4) in the presence of complexes of Pd, Ni, Ru, Co, Mo, W, and Fe. The oxidants in the systems are hypochlorous (HOCl) or hypobromous (HOBr) acids generated from water and halomethanes under the reaction conditions.

SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME 1-HYDROXY-3-AMINOALKYLADAMANTANES AND THEIR DERIVATIVES

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