90814-08-7

Upstream product

• 90865-73-9 2'-O-Tetrahydrofuranyl-2-N-isobutyrylguanosine 
• 72351-28-1 2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide) 
• 90865-73-9 N-{6-Hydroxy-9-[(2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-2-yl]-9H-purin-2-yl}-isobutyramide 
• 86327-76-6 N-{9-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-2-yl]-6-hydroxy-9H-purin-2-yl}-isobutyramide 
• 86327-76-6 5'-O-dimethoxytrityl-2'-O-tetrahydrofuranyl-N-isobutyrylguanosine 

Relevant academic research and scientific papers

SYNTHESIS OF WOBBLE PAIRING OLIGORIBONUCLEOTIDES

Hexaribonucleotides containing inosine at a pairing position adjacent to the other four major nucleosides (GGINCC,N=A,C,G,U) were synthesized in solution by the phosphotriester method using 2'-O-tetrahydrofuranyl protecting groups. 5'-O-dimethoxytrityl-2'

Studies on Transfer Ribonucleic Acids (tRNA) and Related Compounds. XLIX. Solid-Phase Synthesis of Nonadecaribonucleotide Corresponding to the 5'-Half of the Formylmethionine tRNA Deficient in D-Loop and Stem Region

Ribooligonucleotides (nonamer, decamer and nonadecamer) were synthesized by the solid phase phosphotriester method using 2'-O-tetrahydrofuranyl nucleosides.These oligomers were designed in order to obtain E. coli tRNAfMet deficient in D-loop and D-stem and its analogs.Condensation was performed by using dimer blocks and the dimethoxytrityl group on the 5'-hydroxyl group was removed selectively by 1 M ZnBr2 without affecting the 2'-protection.Keywords - solid-phase synthesis; ribooligonucleotide; D-loop deficient tRNA; high pressure liquid chromatography; mobility shift analysis

CHEMICAL SYNTHESIS OF THE 5'-HALF MOLECULE OF E.coli tRNA2Gly

A tritriacontanucleotide which has the sequence of the 5'-half molecule of E.coli glycine tRNA2, was synthesized by the phosphotriester method involving p-anisidate protection for the 3'-phosphate ends.Di- and trinucleotide units were prepared