90819-32-2 Usage
Description
N-Boc-3-hydroxy-D-phenylalanine, also known as Boc-D-OH-Phe-OH, is a chemical compound that belongs to the family of amino acid derivatives. It is a derivative of D-phenylalanine, a naturally occurring amino acid found in protein-rich foods. The "N-Boc" in its name refers to the N-Boc protection group, which is commonly used in organic synthesis to protect the amine group of amino acids. The "3-hydroxy" indicates the presence of a hydroxyl group at the third position of the phenylalanine side chain. This chemical compound is often used in the synthesis of peptide and protein-based drugs, as well as in the development of novel pharmaceuticals and biologically active compounds.
Uses
Used in Pharmaceutical Industry:
N-Boc-3-hydroxy-D-phenylalanine is used as a building block for the synthesis of peptide and protein-based drugs. Its unique structure allows for the creation of novel pharmaceuticals and biologically active compounds with potential therapeutic applications.
Used in Organic Synthesis:
N-Boc-3-hydroxy-D-phenylalanine is used as a protected amino acid in organic synthesis. The N-Boc protection group prevents unwanted side reactions, allowing for the selective modification of the hydroxyl group at the third position of the phenylalanine side chain. This makes it a valuable intermediate in the synthesis of complex organic molecules and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 90819-32-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,8,1 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 90819-32:
(7*9)+(6*0)+(5*8)+(4*1)+(3*9)+(2*3)+(1*2)=142
142 % 10 = 2
So 90819-32-2 is a valid CAS Registry Number.
90819-32-2Relevant articles and documents
Semisynthesis of a Bacterium with Non-canonical Cell-Wall Cross-Links
Chen, Jason S.,Dik, David A.,Schultz, Peter G.,Webb, Bill,Zhang, Nan
supporting information, p. 10910 - 10913 (2020/07/08)
The cell wall is an elaborate framework of peptidoglycan that serves to protect the bacterium against osmotic challenge. This exoskeleton is composed of repeating saccharides covalently cross-linked by peptide stems. The general structure of the cell wall is widely conserved across diverse Gram-negative bacteria. To begin to explore the biological consequence of introducing non-canonical cross-links into the cell wall of Escherichia coli, we generated a bacterium where up to 31percent of the cell-wall cross-links are formed by a non-enzymatic reaction between a sulfonyl fluoride and an amino group. Bacteria with these non-canonical cell-wall cross-links achieve a high optical density in culture, divide and elongate successfully, and display no loss of outer membrane integrity. This work represents a first step in the design of bacteria with non-canonical "synthetic"cell walls.
