908253-55-4Relevant academic research and scientific papers
METHOD OF TREATMENT AND PHARMACEUTICAL COMPOSITIONS
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, (2010/02/16)
The present invention relates to methods, uses, and compositions comprising the caspase inhibitor (R)-N-((2S,3S)-2-(fluoromethyl)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamide, or a pharmaceutically acceptable salt thereof.
Isoxazoline Derivative and Novel Process for Its Preparation
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Page/Page column 7, (2008/12/04)
The present invention relates to an isoxazoline derivative having the cyclic carboxylic acid hemiketal moiety of formula (1) for use as caspase inhibitor, a process for preparing it, and a pharmaceutical composition comprising it.
A NOVEL PROCESS FOR PREPARING 3-AMINO-5-FLUORO-4-DIALKOXYPENTANOIC ACID ESTER
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Page/Page column 19-20, (2008/06/13)
The present invention relates to a novel process for the production of 3-amino-5- fluoro-4-dialkoxypentanoic acid ester used in the precursor of 3-amino-5-fluoro-4- oxopentanoic acid, represented by the following formula (I) : wherein R1 and R2 are as def
ISOXAZOLINE DERIVATIVE AND NOVEL PROCESS FOR ITS PREPARATION
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Page/Page column 16, (2008/06/13)
The present invention relates to an isoxazoline derivative having the cyclic carboxylic acid hemiketal moiety of formula (1) for use as caspase inhibitor, a process for preparing it, and a pharmaceutical composition comprising it.
