90827-97-7Relevant academic research and scientific papers
Controlling Ca2+ Permeable α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Photochromic Ion Channel Blockers
N?rager, Niels G.,Poulsen, Mette H.,Str?mgaard, Kristian
, p. 8048 - 8053 (2018)
Ionotropic glutamate receptors (iGluRs) play a critical role in normal brain function and neurodegenerative diseases. Development of light-dependent compounds would enable studies of iGluRs within intact mammalian neural tissue, as light is noninvasive and can be applied with high spatiotemporal precision. Here we develop a potent photochromic antagonist that selectively targets the Ca2+ permeable AMPA-type of iGuRs, thus providing an important tool to study the contribution of AMPA-type iGluRs on neuronal activity.
SOLVENT AND SUBSTITUENT EFFECTS ON THERMAL CIS-TRANS-ISOMERIZATION OF SOME 4-DIETHYLAMINOAZOBENZENES
Marcandalli, Bruno,Pellicciari-Di Liddo, Livia,Di Fede, Cinzia,Bellobono, Ignazio Renato
, p. 589 - 594 (2007/10/02)
Thermal cis-trans-isomerization of some 4'-substituted 4-diethylaminoazobenzenes has been studied.Substitution in the 4'-position leads invariably to an acceleration of the reaction regardless of the nature of the substituent.Logarithms of kinetic constan
Thermodynamic Analysis of Proton Dissociation Equilibria of Some 4-Diethylaminoazobenzenes in 20 wtpercent Aqueous Methanol Solution
Dubini-Paglia, Ernestina,Marcandalli, Bruno,Liddo, Livia Pelliciari-Di,Leonardi, Cristina
, p. 937 - 940 (2007/10/02)
Proton dissociation of (X = H, CO2H, NO2, OMe; Y = H, Me, OEt) has been examined at 293.15 K in aqueous sulphuric acid solutions.Equilibrium constants for the proton dissociation of (X = H, CO2H, NO2, OMe; Y = H, Me, OEt) have been measured as a function of temperature, in the range 293 - 323 K, in 20 wtpercent aqueous methanol solution.Thermodynamic functions (ΔG0, ΔH0, ΔS0) have been calculated.Experimental data have been discussed and interpreted in terms of linear free energy relationships.Tautomeric equilibrium constants have been evaluated and apparent equilibrium constants separated into the separate contributions of ammonium and azonium forms.
