908297-79-0

Basic information

• Product Name: 1,3-Bis(5-carboxypyridin-2-yl)benzene
• Synonyms: 1,3-Bis(5-carboxypyridin-2-yl)benzene;1,4-Bis(5-carboxypyridin-2-yl)benzene;6-(1H-Indol-6-yl)-nicotinic acid;6-(1-Methyl-1H-indol-5-yl)-nicotinic acid;6-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-nicotinic acid;6-(3-Oxo-3,4-dihydro-2H-benzothiazin-7-yl)-nicotinic acid;6-(Naphthalen-1-yl)-nicotinic acid;6-Benzo[b]thiophen-2-yl-nicotinic acid
• CAS NO: 908297-79-0
• Molecular Formula: C18H12N2O4
• Molecular Weight: 0
• Mol File: 908297-79-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Bis(5-carboxypyridin-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Bis(5-carboxypyridin-2-yl)benzene(908297-79-0)
• EPA Substance Registry System: 1,3-Bis(5-carboxypyridin-2-yl)benzene(908297-79-0)

Safety Data

• Hazardous Substances Data: 908297-79-0(Hazardous Substances Data)

Usage

Type of compound

Chemical compound

Fluorescent property

Yes

Usage

Building block for the synthesis of coordination polymers and metal-organic frameworks

Structural components

Two 2-pyridylcarboxylate groups
One benzene ring

Coordination with metal ions

Allows for the formation of extended networks

Potential applications

Gas storage
Catalysis
Sensing

Additional uses

Creation of luminescent materials
Study of supramolecular chemistry

Upstream product

• 90-14-2 1-Iodonaphthalene 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 90-11-9 1-Bromonaphthalene 

Relevant articles and documents

Regio- and Stereoselective Synthesis of Functionalized Dihydropyridines, Pyridines, and 2H-Pyrans: Heck Coupling of Monocyclopropanated Heterocycles

A palladium-catalyzed coupling between aryl halides and monocyclopropanated pyrroles or furans has been developed, leading to valuable six-membered N- and O-heterocycles. As the key step, a selective cleavage of the non-activated endocyclic C?C bond of the 2-heterobicyclo-[3.1.0]hexane framework is achieved. The developed method offers access to highly functionalized piperidines, pyridines, and pyrans that are challenging to access by traditional methods.

An efficient Negishi cross-coupling reaction catalyzed by nickel(II) and diethyl phosphite

A combination of diethyl phosphite-DMAP and Ni(II) salts forms a very effective catalytic system for the cross-coupling reactions of arylzinc halides with aryl, heteroaryl, and alkenyl bromides, chlorides, triflates, and nonaflates. The choice of solvent is quite important and the mixture of THF-N-ethylpyrrolidinone (NEP) (8:1) was found to be optimal. The reaction usually requires only 0.05 mol % of NiCl2 or Ni(acac)2 as catalyst and proceeds at room temperature within 1-48 h.