90832-27-2Relevant articles and documents
Reduction of β-Lactams, I. Reduction of 3,3,3',3'-Tetramethyl-2,2'-dione with Complex Hydrides
Verkoyen, Carl,Rademacher, Paul
, p. 1659 - 1670 (2007/10/02)
Reduction of the title compound 7 with lithium aluminium hydride leads to four products 8 to 11 in yields depending on the reaction conditions.Compounds 8 to 10 are also obtained from the bicyclic hydrazide 12, isomeric with 7.Therefore, the reduction of 7 and 12 is likely to proceed in part via common intermediates.A reaction scheme is proposed to account for the generation of the products.With other hydride reagents comlex reaction mixtures are obtained from 7.The reduction of 7 to 3,3,3',3'-tetramethyl-1,1'-biazetidine (13) failed.