90832-48-7

Basic information

• Product Name: (3R,4S)-4-Benzyloxymethoxy-3-hydroxy-2-methylene-decanoic acid tert-butyl ester
• CAS NO: 90832-48-7
• Molecular Weight: 392.536
• Mol File: 90832-48-7.mol

Chemical Properties

• CAS DataBase Reference: (3R,4S)-4-Benzyloxymethoxy-3-hydroxy-2-methylene-decanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-4-Benzyloxymethoxy-3-hydroxy-2-methylene-decanoic acid tert-butyl ester(90832-48-7)
• EPA Substance Registry System: (3R,4S)-4-Benzyloxymethoxy-3-hydroxy-2-methylene-decanoic acid tert-butyl ester(90832-48-7)

Safety Data

• Hazardous Substances Data: 90832-48-7(Hazardous Substances Data)

Upstream product

• 88722-74-1 tert-butyl β-(dimethylamino)propionate 
• 88722-71-8 2-<(benzyloxy)methoxy>octan-1-al 
• 74-88-4 methyl iodide 

Relevant articles and documents

High Diastereoface Selection in an Ester Enolate Addition to α-Alkoxy Aldehydes: Stereoselective Synthesis of α-Methylene-β-hydroxy-γ-alkoxy Esters

The aldol-type condensation of β-(dimethylamino)propionates 3 and 4 with a series of α-alkoxy aldehydes proceeds with unprecedented high stereoselectivity (up to 24:1) to give anti α-methylene-β-hydroxy-γ-alkoxy esters.The best results were obtained when the reaction was carried out in diethyl ether and the ester enolate was allowed to equilibrate to the thermodynamically more stable geometric isomer.