90833-63-9

Basic information

• Product Name: 6-Quinoxalinecarboxylic acid, 2,3-bis(3-methoxyphenyl)-
• CAS NO: 90833-63-9
• Molecular Formula: C23H18N2O4
• Molecular Weight: 386.407
• Mol File: 90833-63-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-Quinoxalinecarboxylic acid, 2,3-bis(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Quinoxalinecarboxylic acid, 2,3-bis(3-methoxyphenyl)-(90833-63-9)
• EPA Substance Registry System: 6-Quinoxalinecarboxylic acid, 2,3-bis(3-methoxyphenyl)-(90833-63-9)

Safety Data

• Hazardous Substances Data: 90833-63-9(Hazardous Substances Data)

Upstream product

• 40101-17-5 3,3'-dimethoxybenzil 
• 619-05-6 3,4-diaminobenzoic acid 

Downstream Products

• 90833-57-1 2,3-bis(3-hydroxyphenyl)-6-quinoxalinecarboxylic acid 
• 935293-15-5 C₃₅H₃₀N₄O₆ 
• 935293-06-4 C₃₅H₃₀N₄O₅ 

Relevant articles and documents

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors

A library of quinoxaline derivatives were prepared to target non-structural protein 1 of influenza A (NS1A) as a means to develop anti-influenza drug leads. An in vitro fluorescence polarization assay demonstrated that these compounds disrupted the dsRNA-NS1A interaction to varying extents. Changes of substituent at positions 2, 3 and 6 on the quinoxaline ring led to variance in responses. The most active compounds (35 and 44) had IC50 values in the range of low micromolar concentration without exhibiting significant dsRNA intercalation. Compound 44 was able to inhibit influenza A/Udorn/72 virus growth.

Substituted 5- and 6-quinoxalinecarboxylic acids and their tuberculostatic activity

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