908341-18-4Relevant articles and documents
Molecular tongs containing amino acid mimetic fragments: New inhibitors of wild-type and mutated HIV-1 protease dimerization
Bannwarth, Ludovic,Kessler, Albane,Pèthe, St?phanie,Collinet, Bruno,Merabet, Na?ma,Boggetto, Nicole,Sicsic, Sames,Reboud-Ravaux, Michèle,Ongeri, Sandrine
, p. 4657 - 4664 (2006)
We have designed, synthesized, and evaluated the inhibitory activity and metabolic stability of new peptidomimetic molecular tongs based on a naphthalene scaffold for inhibiting HIV-1 protease dimerization. Peptidomimetic motifs were inserted into one pep