90868-33-0Relevant academic research and scientific papers
2,6-Dimethyl-4-nitrobenzoic anhydride (DMNBA): An effective coupling reagent for the synthesis of carboxylic esters and lactones
Shiina, Isamu,Miyao, Ryo
experimental part, p. 1313 - 1328 (2009/07/05)
Various carboxylic esters are obtained at room temperature in excellent yields with high chemoselectivities from nearly equimolar amounts of carboxylic acids and alcohols using 2,6-dimethyl-4-nitrobenzoic anhydride with triethylamine by the promotion of 4-(dimethylamino)pyridine. The efficiency of the esterification is compared to those of other dehydrations using substituted benzoic anhydrides as coupling reagents. This method was successfully applied to the synthesis of threo-aleuritic acid lactone and the desired 17-membered ring compound was prepared in high yield at room temperature from the corresponding free trihydroxycarboxylic acid using 2,6-dimethyl-4-nitrobenzoic anhydride in the presence of 4-(dimethylamino)pyridine.
On the Nature of Resonance Interactions in Substituted Benzenes. Part 3. A 13C Nuclear Magnetic Resonance Study of Substituent Effects in 4-Substituted Benzamides and Methyl Benzoates in Dimethyl sulphoxide
Dell'Erba, Carlo,Mele, Andrea,Novi, Marino,Petrillo, Giovanni,Sancassan, Fernando,Spinelli, Domenico
, p. 2055 - 2058 (2007/10/02)
The substituent effect on the carbonyl-carbon chemical shift in 4-X-benzamides 2 and in 2,6-dimethyl-4-X-benzamides 2' has been studied in (CD3)2SO.Comparison of the results with those obtained from the corresponding methyl 4-X-benzoates 1 and 1'in the sa
