90868-91-0Relevant academic research and scientific papers
Triazole compound, and application thereof in agriculture
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Paragraph 0139-0147, (2019/12/29)
The invention provides a triazole compound, and an application thereof in agriculture, and concretely provides a compound represented by formula (I), a preparation method thereof, a composition containing the compound, and an application of the compound or the composition as a bactericide. R, X, R, R, n, R, R, R, R, R and R in the formula (I) are as defined in the description.
Catalytic substitution/cyclization sequences of: O -substituted Isocyanates: Synthesis of 1-alkoxybenzimidazolones and 1-alkoxy-3,4-dihydroquinazolin-2(1 H)-ones
Wang, Qiang,An, Jing,Alper, Howard,Xiao, Wen-Jing,Beauchemin, André M.
supporting information, p. 13055 - 13058 (2017/12/15)
O-Substituted isocyanates (O-isocyanates) have rarely been used in organic synthesis, given their tendency to undergo side reactions (e.g., trimerization). Herein, we show that masked (blocked) O-isocyanate precursors allow one-pot or cascade reaction sequences featuring base-catalyzed substitution with 2-iodoanilines and 2-iodobenzylamines followed by copper-catalyzed cyclization, to form benzimidazolones and 3,4-dihydroquinazolin-2(1H)-ones. This work shows that O-isocyanates can serve as efficient building blocks for the synthesis of hydroxylamine-containing heterocycles.
PHENYLQUINAZOLINE DERIVATIVES
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Paragraph 0586; 0587; 0588; 0589, (2013/07/19)
Novel quinazolinamide derivatives of the formula (I), in which R1-R43 and X have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
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Page/Page column 75, (2010/01/29)
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
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, (2009/12/27)
The present invention relates to 3,4-substituted piperidinyl - based renin inhibitor compounds bearing at 4-position lsoqumolone and having the Formula (I) : The invention further relates to pharmaceutical compositions containing said compounds, as well a
NOVEL 3,4-DISUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES
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Page 25, (2010/02/09)
The invention relates to novel 3,4-disubstituted 1,2,3,6-tetrahydropyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including proc
