90868-91-0

Usage

Uses

Used in Scientific Research:
2-BCA is used as a research chemical for studying the effects of serotonin and dopamine on the brain. It helps researchers understand the mechanisms of these neurotransmitters and their role in various neuropsychiatric disorders.
Used in Pharmaceutical Development:
2-BCA has potential applications in the development of pharmaceuticals for the treatment of various neuropsychiatric disorders. Its ability to selectively release serotonin makes it a promising candidate for the development of drugs targeting conditions such as depression, anxiety, and other mood disorders.
Used in Drug Regulation and Control:
Due to its potential for abuse and addiction, 2-BCA is strictly regulated and controlled in many countries. Its use is limited to scientific research and pharmaceutical development, ensuring that it is not misused or abused by individuals seeking recreational effects.

Upstream product

• 143238-84-0 (2-bromophenyl)methyl methanesulfonate 
• 765-30-0 Cyclopropylamine 
• 18982-54-2 o-bromobenzyl alcohol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 1367454-77-0 (2-amino-6-{2-[(cyclopropylmethylamino)methyl]phenyl}quinazolin-4-yl)-(1,3-dihydroisoindol-2-yl)methanone 
• 1247180-19-3 (2-bromobenzyl)cyclopropylmethylamine 

Relevant academic research and scientific papers

Triazole compound, and application thereof in agriculture

The invention provides a triazole compound, and an application thereof in agriculture, and concretely provides a compound represented by formula (I), a preparation method thereof, a composition containing the compound, and an application of the compound or the composition as a bactericide. R, X, R, R, n, R, R, R, R, R and R in the formula (I) are as defined in the description.

Catalytic substitution/cyclization sequences of: O -substituted Isocyanates: Synthesis of 1-alkoxybenzimidazolones and 1-alkoxy-3,4-dihydroquinazolin-2(1 H)-ones

O-Substituted isocyanates (O-isocyanates) have rarely been used in organic synthesis, given their tendency to undergo side reactions (e.g., trimerization). Herein, we show that masked (blocked) O-isocyanate precursors allow one-pot or cascade reaction sequences featuring base-catalyzed substitution with 2-iodoanilines and 2-iodobenzylamines followed by copper-catalyzed cyclization, to form benzimidazolones and 3,4-dihydroquinazolin-2(1H)-ones. This work shows that O-isocyanates can serve as efficient building blocks for the synthesis of hydroxylamine-containing heterocycles.

PHENYLQUINAZOLINE DERIVATIVES

Novel quinazolinamide derivatives of the formula (I), in which R1-R43 and X have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl - based renin inhibitor compounds bearing at 4-position lsoqumolone and having the Formula (I) : The invention further relates to pharmaceutical compositions containing said compounds, as well a

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.

NOVEL 3,4-DISUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES

The invention relates to novel 3,4-disubstituted 1,2,3,6-tetrahydropyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including proc