90869-66-2 Usage
Uses
Used in Chemical Research:
1-(2-chlorophenyl)-2-(methylamino)propan-1-one hydrochloride is utilized as a research chemical for studying its psychoactive and stimulant effects. Its application in this field aids in understanding the compound's mechanisms of action and potential risks associated with its use.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-(2-chlorophenyl)-2-(methylamino)propan-1-one hydrochloride may serve as a starting point for developing new medications targeting the central nervous system. Its structural and functional properties could be harnessed to create novel therapeutic agents, provided that safety and efficacy are thoroughly evaluated.
Used in Regulatory and Forensic Analysis:
As a controlled substance, 1-(2-chlorophenyl)-2-(methylamino)propan-1-one hydrochloride is subject to regulatory monitoring and forensic analysis. It is used as a reference compound in laboratories and institutions responsible for detecting, identifying, and quantifying the presence of this substance in various samples, such as those related to drug enforcement and public health.
Check Digit Verification of cas no
The CAS Registry Mumber 90869-66-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,8,6 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 90869-66:
(7*9)+(6*0)+(5*8)+(4*6)+(3*9)+(2*6)+(1*6)=172
172 % 10 = 2
So 90869-66-2 is a valid CAS Registry Number.
90869-66-2Relevant articles and documents
Systematic Structure-Activity Studies on Selected 2-, 3-, and 4-Monosubstituted Synthetic Methcathinone Analogs as Monoamine Transporter Releasing Agents
Walther, Donna,Shalabi, Abdelrahman R.,Baumann, Michael H.,Glennon, Richard A.
, p. 740 - 745 (2019)
Methcathinone analogs are appearing on the clandestine market at a rate nearly out-pacing the ability of investigators to examine them on an individual basis. To formulate structure-activity relationship (SAR) generalities, we examined the releasing ability of several simple methcathinone analogs at the three monoamine transporters (i.e., the dopamine, norepinephrine, and serotonin transporters, DAT, NET, and SERT, respectively) using in vitro assay methods. The analogs included methcathinone and 14 other compounds monosubstituted at the 2-, 3-, or 4-position. In general, (a) the 2-substituted analogs were less potent than either the 3- or 4-substituted analogs, (b) the 3- and 4-substituted analogs were relatively similar in potency, (c) methcathinone was the most selective as a DAT-releasing agent, and (d) the 3- and 4-CF3 analogs were the least DAT-selective. For the 15 compounds, there was a significant correlation (r > 0.9) between DAT and NET potency, suggesting relatively similar structure-activity relationships (at least for the compounds examined here). Several of the compounds have appeared on the clandestine market since our studies were initiated, and the present results provide new information on how they might act.
