9087-69-8

Basic information

• Product Name: HAPTOGLOBIN, HUMAN
• Synonyms: HAPTOGLOBIN, MIXED TYPE, HUMAN;HAPTOGLOBIN, MIXED TYPE, HUMAN PLASMA;HAPTOGLOBIN (PLASMA/MIXED TYPE);HAPTOGLOBULIN HUMAN;haptoglobins;haptoglobin from human plasma;Haptoglobin from pooled human plasma;Recombinant Human Haptoglobin
• CAS NO: 9087-69-8
• Molecular Formula: NULL
• Molecular Weight: 0
• Product Categories: Haptoglobin;HaptoglobinImmune Cell Signaling and Blood;Proteins of Inflammation;Immune System Regulation;Plasma&Blood Proteins;Plasma, Blood, and Related Proteins and Reagents;proteins
• Mol File: 9087-69-8.mol
• Article Data: 0

Chemical Properties

• Appearance: off-white/powder
• Storage Temp.: 2-8°C
• Solubility: H2O: 10 mg/mL, clear to faintly turbid, colorless to almost
• CAS DataBase Reference: HAPTOGLOBIN, HUMAN(CAS DataBase Reference)
• NIST Chemistry Reference: HAPTOGLOBIN, HUMAN(9087-69-8)
• EPA Substance Registry System: HAPTOGLOBIN, HUMAN(9087-69-8)

Safety Data

• Hazard Codes: B
• WGK Germany: 3
• RTECS: MG8575500
• Hazardous Substances Data: 9087-69-8(Hazardous Substances Data)

Usage

Uses

Haptoglobin was used to study induction of the acrosome reaction in sperm. Exposure to low temperature increases their rate of fusion with zona-free hamster oocytes.

General Description

Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins.The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains.

Biochem/physiol Actions

Functions by binding to plasma hemoglobin (from hemolysis). The complex is removed from the circulation, by binding to CD163 receptors on macrophages, to salvage iron and prevent oxidative damage.