909036-46-0

Basic information

• Product Name: 2-CHLORO-3-IODOPYRIDIN-4-AMINE
• Synonyms: 2-CHLORO-3-IODOPYRIDIN-4-AMINE;2-Chloro-3-iodo-4-aminopyridine;4-Amino-2-chloro-3-iodopyridine;4-PyridinaMine, 2-chloro-3-iodo-;2-Chloro-3-iodo-4-pyridinamine
• CAS NO: 909036-46-0
• Molecular Formula: C₅H₄ClIN₂
• Molecular Weight: 254.46
• Mol File: 909036-46-0.mol
• Article Data: 18

Chemical Properties

• Melting Point: 116-117℃
• Boiling Point: 377.042 °C at 760 mmHg
• Flash Point: 181.829 °C
• Appearance: White to pink/orange/Solid
• Density: 2.139g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.708
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 2.96±0.42(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2-CHLORO-3-IODOPYRIDIN-4-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-IODOPYRIDIN-4-AMINE(909036-46-0)
• EPA Substance Registry System: 2-CHLORO-3-IODOPYRIDIN-4-AMINE(909036-46-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 909036-46-0(Hazardous Substances Data)

Usage

Uses

2-Chloro-3-iodo-4-pyridinamine can be used as a useful synthetic intermediate.

InChI:InChI=1/C5H4ClIN2/c6-5-4(7)3(8)1-2-9-5/h1-2H,(H2,8,9)

Upstream product

• 14432-12-3 4-Amino-2-chloropyridine 

Downstream Products

• 1251041-78-7 4-(3′,5′-dimethylphenyl)-3-azadibenzothiophene 

Relevant articles and documents

Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols

A library of 16 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols 17–32 has been synthesized for use in biological testing against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. The 4-substituted 2-(1H-pyrrolo[3,2-c]pyridi

Organic compound, electroluminescent device containing organic compound and applications of electroluminescent device

The invention discloses an organic compound with a structure represented by a formula (I), wherein the LUMO energy level of the compound is reduced by linking an aza aromatic ring structure (a structure represented by a formula (II)), so that the electronic conductivity of the material is improved, and the compound is suitable for being used as an electronic material (such as an electron transportmaterial, an electron injection material, a hole blocking material and the like). According to the invention, the organic compound as an electron type material, particularly an electron transmissionmaterial, can be matched with hole type materials (such as a hole transmission material, a hole injection material and an electron blocking material), so that the transmission of electrons and holes is balanced, and the service life of a device is prolonged.

HETEROARYL SUBSTITUTED AMINOPYRIDINE COMPOUNDS

Disclosed are compounds of Formula (I) or salts thereof, wherein HET is a heteroaryl selected from pyrrolo[2,3 b]pyridinyl, pyrrolo[2,3 d]pyrimidinyl, pyrazolo[3,4 b]pyridinyl, pyrazolo[3,4 d]pyrimidinyl, imidazolo[4,5 b]pyridinyl, and imidazolo[4,5 d]pyrimidinyl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a nitrogen ring atom in said heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; A is pyrazolyl, imidazolyl, triazolyl, isoxazolyl, oxadiazolyl or dihydroisoxazolyl, each substituted with zero or 1 Ra; and R3, Ra, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.