90909-78-7

Basic information

• Product Name: 3H-Pyrrolizine-2-carboxylic acid, 3-phenyl-, ethyl ester
• CAS NO: 90909-78-7
• Molecular Formula: C16H15NO2
• Molecular Weight: 253.301
• Mol File: 90909-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3H-Pyrrolizine-2-carboxylic acid, 3-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrrolizine-2-carboxylic acid, 3-phenyl-, ethyl ester(90909-78-7)
• EPA Substance Registry System: 3H-Pyrrolizine-2-carboxylic acid, 3-phenyl-, ethyl ester(90909-78-7)

Safety Data

• Hazardous Substances Data: 90909-78-7(Hazardous Substances Data)

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 13507-49-8 2-(diethoxyphosphoryl)-3-phenylacrylic acid ethyl ester 

Relevant articles and documents

On the Reaction of 2-Pyrrolecarbaldehyde with Hetero-substituted Ethenes

3H-Pyrrolizines 1 have been obtained from reactions of 2-pyrrolecarbaldehyde with ethenylphosphonates 2 and the phosphane oxide 5, respectively, the ratio of products depending on the structure of the educts.On varying the reaction conditions a controlled synthesis of both isomers 1e/f was achieved.Pyrrolizines, formed in a reaction of 2-pyrrolecarbaldehyde with ethenyl phenyl sulfone (3), could not be isolated since the reaction proceeded to give more complex pyrrolizine derivatives and the cyclazine 11.A mechanism is proposed for this multistep reaction.N-Alkylatio n of 2-pyrrolecarbaldehyde with dihaloalkanes has been carried out using phase transfer catalysis.