909110-49-2Relevant academic research and scientific papers
Synthesis of homoallylic amines via the palladium-catalyzed decarboxylative coupling of amino acid derivatives
Burger, Erin C.,Tunge, Jon A.
, p. 10002 - 10003 (2007/10/03)
Protected homoallylic amines are synthesized by the decarboxylative coupling of α-amino acid derivatives. The catalytic C-C bond-forming reaction relies on the bioinspired decarboxylative metalation of α-amino acids to produce α-amino anion equivalents. The α-amino anion equivalents are intercepted by π-allyl palladium electrophiles to produce substituted homoallylic amines. Copyright
