909117-05-1

Basic information

• Product Name: 2-Propenamide, 2-(acetylamino)-N-(1-methylpropyl)-
• Synonyms: 2-Propenamide, 2-(acetylamino)-N-(1-methylpropyl)-
• CAS NO: 909117-05-1
• Molecular Formula: C9H16N2O2
• Molecular Weight: 0
• Mol File: 909117-05-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Propenamide, 2-(acetylamino)-N-(1-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, 2-(acetylamino)-N-(1-methylpropyl)-(909117-05-1)
• EPA Substance Registry System: 2-Propenamide, 2-(acetylamino)-N-(1-methylpropyl)-(909117-05-1)

Safety Data

• Hazardous Substances Data: 909117-05-1(Hazardous Substances Data)

Usage

Classification

Acrylamide

Usage

Commonly used in industrial and laboratory settings as a monomer for polymer and copolymer production.
Used as a starting material for synthesizing pharmaceuticals and agrochemicals.

Safety Concerns

Requires careful handling due to potential toxic effects on human health and the environment.

Upstream product

• 33966-50-6 SEC-BUTYLAMINE 
• 5429-56-1 N-Acetamidoacrylic acid 

Relevant articles and documents

Evaluation of rat kidney aldose reductase inhibitory activity of some N-acetyl dehydroalanine derivatives

Aldose reductase (AR) is an enzyme that catalyzes the conversion of glucose to sorbitol, which is in turn converted to fructose by sorbitol dehydrogenase. Increased AR activity has been implicated in the pathogenesis of diabetic complications such as neuropathy, nephropathy, retinopathy, and cataract. Inhibitors of AR thus seem to have the potential to prevent or treat diabetic complications. At present, however, side effects and/or insufficient pharmacokinetic profiles have made most of the drug candidates undesirable. In this study, the synthesis (l-o) and ARI activity of 15 N-acetyl dehydroalanine derivatives (a-o) are described. The synthesized compounds mainly contained aliphatic and aromatic side chains. The insertion of ethyl and chloro propyl side chains were shown to be more effective than the rest of the compounds. Between the synthesized compounds N-ethyl (b) and N-propylchloride (h) derivatives showed the best ARI activities.